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Laboratory Study to Evaluate a Pressurized Metered Dose Inhaler with Valved Holding Chamber Use Scenario in COVID-19 Situation where pMDIs in Short Supply

young girl using inhaler with spacer over top of medical professionals in blue background
Conclusions
  • The most efficient and effective delivery method remains that recommended in the device IFU (one actuation inhaled at a time, as well inhalation as soon as possible after actuation)
  • However, this laboratory-based study has indicated that a modified common-canister protocol with an anti-static VHC as the aerosol transfer vehicle has the potential to be a viable ‘off-label’ proposition in hospital situations where there is an urgent need to conserve pMDI medication as well as avoid cross-contamination from pathogenic viruses or bacteria