Metered Dose Inhaler (MDI) with Valved Holding Chamber (VHC) vs Dry Powder Inhalers (DPIs): Using Functional Respiratory Imaging (FRI) to Assess Modelled Lung Deposition in an Asthmatic patient.

Conclusions

• The FRI deposition profiles highlight that the MDI/ AeroChamber Plus* Flow Vu* VHC system delivered an appreciably greater percentage of drug to the lung region than either of the two DPIs.
• The influence of inhalation flow profile was less with the MDI/VHC system and differed between the two DPIs.