November 24, 2017

Assessing Different Valved Holding Chambers with Facemask for Delivered Mass to Carina with Inhaled Corticosteroid by Pressurized Metered-Dose Inhaler

Poster presented at BTS 2017 in London, UK.

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  • In vitro study evaluated performance of the following chambers with facemask: AeroChamber Plus* Flow-Vu* VHC, Vortex, A2A, OptiChamber Diamond, Pocket Chamber, Compact Space Chamber plus and Volumatic
  • Significantly more fluticasone propionate MDI medication was delivered with the AeroChamber Plus* Flow-Vu* chamber compared to the other chambers evaluated
  • The study highlights the impact of differences in chamber design and facemask fit upon drug delivery, and therefore the potential risk of interchanging chambers without understanding the impact of doing so
  • This study can be used when educating health care providers that chambers are not all equivalent


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